ABSTRACT
Background: Diabetes mellitus is a multisystem disorder associated with number of complications. If patients are to contribute to the effective control of diabetes, awareness and practices can assist in reducing the incidence of its complications.Methods: A cross-sectional study of 200 type II diabetic patients at JSS Hospital, Mysuru was conducted, assessment of health seeking behaviour using semi structured questionnaire was done. Quality of life was assessed using WHO QOL-BREF Questionnaire.Results: Among 200 study participants 53.5% belongs to age group 41-60, 57.5% were males, 44.5% were having family history of diabetes, 68.5% were on oral hypoglycemic agents. 163 (81.5%) were anxious when they were diagnosed as diabetics, 123 (61.5%) were influenced by themselves to go for investigations, 68 (34%)were influenced by Doctors, 131 (65.5%) had no money as the barrier to attend hospital for check-up, 186 (93%) visit hospital once in less than 3 months, 180 (90%) of them believed oral drugs are the treatment for diabetes, 188 (94%) prefer Allopathic medicine. Association between initial response on diagnosis and interval for regular monitoring with Quality of life of diabetic patients was statically significant (p?0.05).Conclusions: Health seeking behaviour is an important determinant of controlled glycaemic status and Quality of life of people living with diabetes.
ABSTRACT
Background: Cardiovascular diseases (CVD) are leading cause of death among non-communicable diseases (NCD). Many people in developing countries are detected late and die from NCDs, often in their most productive years. Prevention of CVD is an essential step to control the epidemic of NCDs. Thus, this study was undertaken to assess the prevalence of risk factors and to estimate the risk of CVD in the next 10 years.Methods: A community based cross-sectional study was conducted among 608 individuals aged ≥40 years in rural area of Mysuru. Data was collected using Semi structured questionnaire and 10 year CVD risk was estimated using World Health Organization/International Society of Hypertension (WHO/ISH) risk prediction charts.Results: A total of 608 study participants (mean age 56.76±11.07 years; Male:Female ratio 1.2:1) were included in the study. The prevalence of tobacco (32.9%) and alcohol (20.1%) consumption was significantly higher among males compared with females. Hypertension, diabetes and obesity prevalence was 39.5%, 15.5% and 28.1% respectively. One-fifth of population had moderate (20-39%) estimated risk and 7.4% had very high (≥40%) risk of developing CVD event in next 10 years. The estimated high risk (≥30%) of CVD events was statistically higher among individuals who were non-literates, unemployed, physically inactive, middle and above socioeconomic status.Conclusions: In the present study, CVD risk factors and estimated risk of CVD were significantly prevalent in the rural population. The use of simple tools like WHO/ISH risk prediction charts to estimate CVD risk is recommended in low resource settings at Community level, as the benefit of screening outweighs the risk of missing an opportunity to prevent CVD.
ABSTRACT
Dietary alterations were used to demonstrate selective handling of fatty acids during their redistribution in vivo. Differences in the mol per cent of individual acyl chains in the non-esterified fatty acid, acyl-coenzyme A and phospholipid fractions reflected a result of relative precursor abundance combined with enzymic selectivities. Selective distributions were observed in the utilization of individual acyl chains between 16:0 and 18:0, 18:1 and 18:2, and among 20:3, 20:4 and 20:5, 22:6 by ligase(s), hydrolase(s) and acyl-transferases. The variations in the mol per cent of linoleate present in the acyl-coenzyme A fraction of liver relative to that in the non-esterified fatty acids suggested an in vivo regulation of the level of linoleoyl-coenzyme A that influenced the synthesis of both arachidonoyl-coenzyme A and lipids. The greater abundance of eicosapentaenoic acid in the free fatty acid fraction relative to that in the acyl-coenzyme A fraction may increase the ability of dietary 20: 5n-3 to be an effective inhibitor of the synthesis of prostaglandins derived from 20:4n-6.